Gas canister man storms office

One of the country's busiest shopping streets has been closed as a man wearing gas canisters stormed into an office and threatened to blow himself up, it was reported. Tottenham Court Road in central London was closed after police received emergency calls at midday. Scotland Yard sent a hostage negotiator to the scene amid reports the man had held people hostage inside the building several floors up. Pictures emerged of computer and office equipment being thrown through one of the office windows. A police spokesman said it was "too early to say if the suspect was armed or indeed had taken any hostages" but businesses and nearby buildings were evacuated. Joaqam Ramus, who works at nearby Cafe Fresco, said before being evacuated: "There was talk of a bomb and somebody having a hostage in a building. "All Tottenham Court Road is closed and so are we - the police told us to shut. "We don't know what it is but it seems someone has a hostage."

Read More

Credit card fraud websites shut down on three continents

Three men have been arrested and 36 criminal websites selling credit card information and other personal data shut down as part of a two-year international anti-fraud operation, police have confirmed. The Serious Organised Crime Agency (SOCA), working with the FBI and US Department of Justice, as well as authorities in Germany; the Netherlands; Ukraine; Australia and Romania, swooped after identifying the sites as specialising in selling card and bank details in bulk. The move comes as a blow to what is a growing black market for stolen financial data. Detectives estimated that the card information seized could have been used to extract more than £500m in total by fraudsters. SOCA claimed it has recovered more than two and a half million items of compromised personal and financial information over the past two years. “The authorities have shut down 36 websites but it is difficult to know how many other people had access to that data. They could spring back up somewhere else if a gang is not eradicated completely,” said Graham Cluley of internet security firm Sophos. He added: “This is big business and, just as in any legitimate company there are people who specialise in different things, so there are those who actually get their hands on the personal data and those who sell it on; they are not often the same person.” An investigation by The Independent last summer found that scammers were making a “comfortable living” getting their hands on sensitive information and selling it online. Card details were being offered for sale for between 4p and £60 per card – depending on the quality – according to one source in the business. Some cards would be sold with incomplete or unreliable information; others ready to use. Some of the card details for sale on the websites shut down by SOCA were being sold for as little as £2 each. Investigators said that the alleged fraudsters were using Automated Vending Carts, which allowed them to sell large quantities of stolen data. They are said to be a driver of the growth in banking fraud over the last 18 months because of the speed with which stolen data can be sold. Lee Miles, Head of Cyber Operations for SOCA said: “This operation is an excellent example of the level of international cooperation being focused on tackling online fraud. Our activities have saved business, online retailers and financial institutions potential fraud losses estimated at more than half a billion pounds, and at the same time protected thousands of individuals from the distress caused by being a victim of fraud or identity crime.” An alleged operator in Macedonia was one of those arrested, while two British men accused of buying the information were also detained. Britain’s Dedicated Cheque & Plastic Crime Unit also seized computers suspected of being used to commit fraud.

Read More

Mike Tyson has for the first time revealed his lowest point ever in a searingly candid interview.

Once known as the ‘baddest man on the planet’, his life has taken more than a few dark twists and turns.

But now Mike Tyson has for the first time revealed his lowest point ever in a searingly candid interview.

The former heavyweight champion said that back in 2009 he was in a hotel room with seven prostitutes, a morphine drip in his arm, a pile of cocaine and a bottle of cognac when he began to feel paranoid.

Candid: The former world champion gave his most honest interview yet - revealing the drug-fuelled night that made him turn his life around and get clean and sober

Convinced the women were trying to steal from him he started beating them up and threw them out - to stop them from 'taking his soul'.

 

 Tyson said: ‘That’s when I realised it wasn’t just demons - it was the devil himself.

‘It was the lowest point of a very low life, but it was my own knockout punch to clean up life, get whole, get well - and I haven’t done anything in three years now. 

‘I’m clean. I’m sober.’

Tyson’s recently swapped the boxing ring for the cabaret stage in a six night comedy show at the MGM Grand Casino in Las Vegas, where some of his biggest fights took place.

World Champion: Mike Tyson lands the knockout punch to the jaw of challenger Larry Holmes during fourth round of the World Heavyweight Championship in Atlantic City 1988

 

In an interview with Las Vegas Weekly to promote the show, he was asked to talk about the moment he realised he had to turn his life around.

Tyson, 45 said: ‘Laying in bed in a hotel room - I try never to be alone, even if it’s a prostitute, a dog. 

‘This is really dark. I am in my hotel suite, I’ve got seven women there, and I have a morphine drip, and I had my cocaine, and I had my (Viagra like pill) Cialis, I had my marijuana, I had the Hennessy, and I am at my lowest point because I got paranoid and I thought these women were trying to rob me and set me up. 

‘I started beating them. I was in a dark place. There was a purpose, though, because I didn’t want to give them any more of my soul.

‘So this is my devil, this is where I am, I am locked up alone. There is nobody there telling me that I’m doing too much. 

Troubled: Tyson's first marriage to actress Robin Givens fell apart amid allegations of him being violent - he is now married for the third time

 

Mug shot: In 1992 Tyson was jailed for raping Desiree Washington - a beauty pageant contestant - he was released from prison after three years

‘That is the devil, he won. I kicked them all out. So that was my lowest point. Oh, man. I am just very grateful to be here - my heart should have blown apart. I was sweating wide awake. No more cocaine. No more. Three years clean.’

In his turbulent life Tyson has been married three times, fathered eight children and became the youngest heavyweight champion the world has ever seen at just 20.

But fame ruined him and his troubled upbringing - his mother was a prostitute and he never knew his pimp father - came back to haunt him.

In the interview he claimed to have earned $300million in winnings but admitted that he was so bad with money he was ‘forced to live paycheck to paycheck’.

In 1992, three years after his first marriage to actress Robin Givens fell apart, he was jailed for six years for raping Desiree Washington, a contestant in the Miss Black America pageant.

Released having served three years, he fought Evander Holyfield in the fight that became one of the most notorious bouts in boxing history when he bit part of his opponent’s ear off.

Reflecting on his life Tyson told Las Vegas Weekly that he was now the happiest he has ever been, and is just trying to be a good husband to his third wife, and a good father to his children.

Tyson said: ‘In order to wear the crown, you have to have a miserable life, and that is the one that inherits the crown. 

‘I don’t know, you have to go from the worst to reach the best. I’m just that extreme type of person. That is who I am, the guy that has no limits.’

Read More

EU condemns Repsol state seizure

 The European Parliament has passed a resolution condemning a nationalisation that has strained relations between Spain and Argentina. Argentina has nationalised YPF, wiping out the Spanish firm Repsol's controlling-stake in the oil firm. The resolution asks the European Commission to consider a "partial suspension" of tariffs that benefit Argentine exports into the EU. Shares in Repsol has another decline, falling 2.3% on Friday. Over the week, Repsol stock has lost almost a fifth of its value. MEPs in the European Parliament said the institution "deplores" the decision taken by Argentina and describes it as an "attack on the exercise of free enterprise". Decisions such as that taken by the Argentine authorities "can put a strain on the climate of understanding and friendship needed to reach" a trade agreement between a South American bloc and the EU, it said. The resolution, which is non-binding, received 458 votes in favour, 71 against and 16 abstentions. 'Not valid' It also emerged that Repsol may be obliged to buy a minority shareholder's YPF stake if it ever lost majority control, which Repsol denied. Twenty-five percent of YPF is owned by Argentina's Eskenazi family through its firm, Peterson. Continue reading the main story Nationalising YPF Spain's Repsol has hitherto owned 57.4% of shares with 25.5% belonging to Argentina's Petersen, 0.02% to the Argentine government and 17% traded on stock exchanges The Argentine government proposes to seize 51% of the shares, all of which will be taken from Repsol's stake, leaving the Spanish firm with 6.4% The expropriated shares will in turn be divided between the Argentine government and provincial governors Following the expropriation, Petersen will retain its 25.5% stake and 17% of the shares will continue to be traded Argentina's risky energy seizure According to regulator filings of a 2008 agreement, Repsol must "maintain directly or indirectly through controlled companies an ownership interest greater than or equal to 50.1%". If it does not, Repsol is obliged to buy back the loans used to secure the Eskenazis' shares. But Repsol told the BBC that the expropriation of its stake in YPF had invalidated the agreement. "The agreement is not valid under Spanish law in these conditions," said Kristian Rix, a Repsol spokesman. "The law is unequivocal, there is no debate." Trade war brewing? Spain has threatened retaliation against Argentina over the forced nationalisation of oil firm YPF, raising the prospects of a trade war between the nations. Spanish Trade Secretary Jaime Garcia Legaz said the European Union would intervene over Argentina's seizure of YPF. Argentina is taking over 51% of YPF, wiping out Repsol's 57.4% majority stake. The move has wide support in Argentina but has provoked outrage in Spain. Spain's Foreign Minister Jose Manuel Garcia-Margallo said US Secretary of State Hillary Clinton had also offered support. Repsol has said it wants around $10bn (£6.2bn) for its stake in YPF, but Argentina has said it does not accept that valuation. YPF, Argentina's biggest oil company, was privatised in 1993. Last year it announced huge new finds of shale oil and gas.

Read More

British police arrested three people, including the royal editor of Rupert Murdoch's Sun tabloid

British police arrested three people, including the royal editor of Rupert Murdoch's Sun tabloid, a source familiar with the situation said, in an escalation of a long-running phone hacking scandal which reaches into Britain's political establishment.

Thursday's arrests and the fact they stemmed from information given to the police by Murdoch's company itself is likely to reignite tensions within the media group, just days before parliament gives its verdict on how the culture of illegality came about.

Next week Rupert Murdoch and son James will also appear before a judicial inquiry to answer questions over the conduct of the press, which will focus on the close ties between Murdoch, his executives and the political establishment.

James Murdoch will appear in court room 73 at the Royal Courts of Justice on Tuesday while lawyers at the inquiry have cleared a day and a half to grill the 81-year-old Rupert on Wednesday and Thursday.

"This was always going to be an important six weeks in this affair, with the Murdochs and politicians going before the Leveson judicial inquiry, but it will be exacerbated by the arrests and the imminent committee report," said Steven Barnett, communications professor at the University of Westminster.

Police made the arrests one day after prosecutors confirmed they had started to examine the police case against four journalists and seven others to establish whether they should be charged with a range of offences including perverting the course of justice.

Press reports have speculated that one of those named in the files is Rebekah Brooks, a former editor of the News of the World and Sun tabloids and a close friend of both Murdochs and Prime Minister David Cameron.

Brooks has been arrested twice, once for corruption and intercepting communications, and more recently for perverting the course of justice, along with her husband, Charlie Brooks.

The three arrested on Thursday were detained at dawn and questioned over inappropriate payments made to police and public officials.

The source familiar with the situation said one of those was Duncan Larcombe, royal editor and a former defence correspondent at the Sun, Britain's biggest selling daily newspaper.

A spokeswoman for Murdoch's British newspaper arm News International confirmed that one of those arrested was a Sun journalist but declined to give further details.

Larcombe was previously a defence correspondent at the Sun and another person arrested on Thursday was described by police as a 42-year-old former member of the armed forces. A woman aged 38 has also been arrested on suspicion of aiding and abetting misconduct in a public office.

ROUTINE HACKING

Murdoch's British newspaper arm has been rocked in the last year by allegations that journalists at the Sun's sister title, the News of the World, had routinely hacked into phones to generate salacious front-page stories.

The police investigation, which forced the closure of the 168-year-old News of the World, has since moved on to the Sun newspaper and whether its journalists paid police and public officials for stories.

While damaging the reputation of Murdoch, the intense spotlight has also revealed the extremely close links he and his executives have with politicians and senior police officers, embarrassing many with tales of horse rides and Christmas drinks between the upper echelons of Murdoch executives and politicians.

Police said the latest arrests were prompted by information provided by the Management and Standards Committee, a small team set up by Murdoch's News Corp to co-operate closely with the police in a move that has infuriated newspaper staff.

The 81-year-old Murdoch was forced to travel to London in February to reassure journalists of his commitment to the Sun after a string of earlier arrests caused a showdown at the paper by staff who felt they had been abandoned by their management.

Since then, the Sun has launched a Sunday version and both the Sun and Murdoch's Times newspaper have noticeably hardened their position towards the government, which turned on Murdoch at the height of the hacking scandal last year.

That antagonism is likely to be exacerbated in the coming weeks when the parliamentary select committee, which summoned James and Rupert Murdoch at the height of the scandal last year, publishes its findings.

The committee investigated allegations of phone hacking after they first surfaced in 2006 and it has since looked at whether it was misled in its initial inquiry by a host of News International executives who pleaded innocence.

Paul Farrelly, a leading member of the committee, told Reuters they hoped to publish the long-awaited report by May 1.

Tom Watson, a member of the committee who has campaigned against Murdoch, told reporters he thought News Corp had become a toxic institution which operated like a shadow state

Read More

Diddy tops hip-hop rich list

Rap mogul and entrepreneur Sean 'Diddy' Combs has topped Forbes magazine's annual hip-hop rich list. The star is worth $550 million, according to the publication. New dad Jay-Z comes in second with an estimated $460 million fortune. Coachella festival headliner Dr. Dre, Bryan 'Birdman' Williams and 50 Cent round out the top five.

Read More

Surf Air: Can an all-you-can-fly airline possibly work?

 

SURF AIR, a Californian start-up, has a novel business model: for a monthly fee you can fly with the airline as much as you want. Is buffet-style air travel the wave of the future? JetBlue and Sun Country Airlines have both already tried offering all-you-can-fly passes, but so far no carrier has built its business model exclusively on a buffet plan. The idea isn't bad, but some scepticism is warranted. At $790 a month, Surf Air's flying plan will probably only appeal to business travellers who often go to the same places and rich Californians in long-distance relationships. Will that customer base allow Surf Air to make a profit? Maybe: 20m frequent flyers jetted between San Francisco and Los Angeles in 2011, according to the company's numbers. The airline plans to launch with service between Palo Alto, Monterey, Santa Barbara and Los Angeles, but it still needs to secure regulatory approval, according to a company press release. Frequent flyers make up a huge portion of the business-traveller population, and almost every airline relies on business travellers to get (and stay) in the black. There is surely some group of private-jet-sharing business travellers who might be attracted to an all-you-can-jet airline as a cheaper alternative. A lot will depend on how many flights and how much convenience Surf Air can offer, and how quickly it can expand service. The company's promises certainly seem attractive: [Surf Air will offer] its members 30-second booking and cancellations, travel to and from uncongested regional airports, and an easy arrive-and-fly process with no hassle, no lines and no extra fees. It's easy to make promises, though. It's much harder to run a profitable airline. As Gulliver often notes, the American airline sector overall has never really made any money—in fact, total earnings over the entire history of the industry are minus $33 billion. That, of course, suggests that existing airlines might be doing it wrong. Maybe all-you-can-fly really is the way to go. It's at least worth a shot. I'll be eager to see what people think of the final product—assuming regulators give the go-ahead.

Read More

Worrying is good for you and reflects higher IQ

It evolved in humans along with intelligence to make them more adept at avoiding danger. A study of 42 people found the worst sufferers of a common anxiety disorder had a higher IQ than those whose symptoms were less severe. Scientists say their findings published in Frontiers in Evolutionary Neuroscience, suggest worrying has developed as a beneficial trait. Psychiatrist Professor Jeremy Coplan, of SUNY Downstate Medical Centre in New York, and colleagues found high intelligence and worry are linked with brain activity measured by the depletion of the nutrient choline in the white matter of the brain. He said: "While excessive worry is generally seen as a negative trait and high intelligence as a positive one, worry may cause our species to avoid dangerous situations, regardless of how remote a possibility they may be. "In essence, worry may make people 'take no chances,' and such people may have higher survival rates. Thus, like intelligence, worry may confer a benefit upon the species." The researchers made the discovery by monitoring activity in the brains of twenty six patients with generalized anxiety disorder (GAD) and eighteen healthy volunteers to assess the relationship between IQ, worry and the metabolism of choline. In the control group high IQ was associated with a lower degree of worry, but in those diagnosed with GAD it was linked with more. The correlation between IQ and worry was significant in both the GAD group and the healthy control group. But in the former it was positive and in the latter negative. Previous studies have indicated excessive worry tends to exist both in people with higher and lower intelligence, and less so in people of moderate intelligence. It has been suggested people with lower intelligence suffer more anxiety because they achieve less success in life. Worrying has also been shown to lessen the effect of depression by countering brain activity that heightens the condition.

Read More

Eating nuts can help stave off obesity, says study

 

Dieters often dismiss them because of their high fat content, but research suggests that snacking on nuts can help keep you slim. A study found that those who consumed varieties such as almonds, cashews and pistachios demonstrated a lower body weight, body mass index (BMI) and waist circumference compared to non-consumers. They were also at lower risk of developing heart disease, type 2 diabetes and metabolic syndrome. Experts are now recommending a daily intake of 1.5 ounces, or three tablespoons of nuts as part of a healthy diet. Lead researcher Carol O'Neil, from Louisiana State University, said: 'One of the more interesting findings was the fact that tree nut consumers had lower body weight, as well as lower body mass index (BMI) and waist circumference compared to non-consumers. 'The mean weight, BMI, and waist circumference were 4.19 pounds, 0.9kg/m2 and 0.83 inches lower in consumers than non-consumers, respectively.' In the study, published in the Journal of the American College of Nutrition, researchers compared risk factors for heart disease, type 2 diabetes and metabolic syndrome of nut consumers versus those who did not consume nuts.

Read More

Sony Confirms 10,000 Layoffs In Major Reorganization

 

Confirming the report from earlier this week, Sony president and CEO Kazuo Hirai said the company will cut 10,000 jobs globally as part of a big “One Sony” reorganization. The company has five immediate goals: it wants to strengthen its core businesses — digital imaging, gaming and mobile — turn around its TV business, expand into emerging markets, create new businesses and fuel innovation and, finally, realign the business portfolio and optimize its resources. The 10,000 layoffs and the management shuffling (Kazuo Hirai replaced Howard Stringer as president and CEO in February 2012) pretty much cover that last bit. The details on strengthening its core businesses include a lot of consolidation — for example, Sony will integrate its smartphone, tablet and VAIO businesses, and reduce the number of product models in its TV business. As for innovation, Sony is entering medical technology and life science industry, and it plans to “aggressively promote” 4K technology, which brings four times the resolution of Full HD. We’ll see 4K-enabled products in pro equipment, but Sony also promises to bring the technology into the high-end consumer product segment, which means our brand new Full HD TVs might look obsolete in a couple of years. All of these will cost around $926 million, and Sony projects it will result in net sales of 6 trillion yen ($74 billion) and an operating income margin of 5% in its electronics business by 2014.

Read More

Trolling Could Get You 25 Years in Jail in Arizona

 

 Trolling Could Get You 25 Years in Jail in Arizona One of the Internet's basic tenets—the right to be as much of a myopic, infantile asshat as humanly possible—is currently under attack in Arizona. A sweeping update to the state's telecommunications harrasment bill could make naughty, angry words a Class 1 misdemeanor. Or worse. It's a dangerous precedent, yet another bill written and supported by legislators who fundamentally don't understand the nature of the internet. And I'm not just being a, well, you know. Arizona House Bill 2549 passed both legislative houses last Thursday and is now awaiting approval from Arizona's governor Brewer. The statute states that: "It is unlawful for any person, with intent to terrify, intimidate, threaten, harass, annoy or offend, to use a ANY ELECTRONIC OR DIGITAL DEVICE and use any obscene, lewd or profane language or suggest any lewd or lascivious act, or threaten to inflict physical harm to the person or property of any person." Emphasis added. If the electronic devices and means are employed to stalk a victim, the penalty bumps up to a Class 3 felony. For those not intimately familiar with Arizona penal law, a Class 1 misdemeanor is punishable by a $2,500 fine and up to six months in jail (it's the most aggressive misdemeanor charge the state can bring). A Class 3 felony, meanwhile, carries a minimum sentence of 2.5 years for non-dangerous offenders with no prior record. And a max of 25 years in jail. Opponents of the bill argue that the wording is overly broad and could easily be interpreted to include not just one-on-one communications but public forums like 4Chan, Reddit, and anywhere else that allows commenting. You thought the banhammer was bad? Try handcuffs. It could also have a chilling effect on free speech by prohibiting shocking or "profane" language online. And since the bill stipulates that the offense only has to occur on Arizona soil (since a Facebook comment is definitely a geographic place, right?) that basically puts the entire Internet on notice. The bill's supporters argue that the steps are necessary to prevent online bullying. Despite the public outcry, the bill has seen very little resistance from elected officials. However, given how well Arizona's other recent, short-lived, and generally draconian propositions—-including its racial profiling, anti-gay adoption, and anti-immigration bills—-have fared, House Bill 2549 might not be a law for long, assuming Governor Brewer even signs it.

Read More

New info about statin safety affects millions

U.S. Food and Drug Administration issued new safety information about these cholesterol-lowering drugs that are prescribed to millions of Americans to lower the risk of heart disease. If you're among them, you should understand what the FDA's new guidance means for your health. "Before anyone gets too concerned, you should know that statins are so widely used because they have a long track record of safety and effectiveness," says Dr. Mark Taber, a cardiologist with SSM Heart Institute at St. Joseph Health Center. "All in all, statins have a very high benefit to risk ratio. The widespread use of the drugs, when indicated, probably accounts to a significant degree for the improvement in life expectancy in this country." The FDA called attention to the threat of liver damage as a rare side effect of statins and advised that regular liver enzyme testing is no longer considered useful in predicting or preventing liver injury. "Actually, in general they liberalized the follow up needed for liver function tests on patients taking statins, due to the very low incidence of true liver issues," Taber says. The main warnings related to a slightly higher incidence of developing diabetes while on statins, and a poorly substantiated claim that statins could result in cognitive impairment. Taber points out that cognitive problems, such as confusion or memory problems, were not documented in clinical studies, only by patient reports to the FDA website. "By stating these concerns, the FDA is raising awareness about the potential side effects of statins, but cardiologists already know that there are inherent risks, and we monitor patients appropriately to help ensure that side effects do not occur or are dealt with quickly," Taber notes. "If there is any evidence of a side effect that could be problematic, we can change the medication. But the fact remains that it's important to decrease risk of heart disease, and for many people statins are needed when diet and exercise alone don't result in acceptable cholesterol levels." Whenever a new prescription medication is started, you should look over the package insert to learn about potential side effects. Signs of liver damage, for instance, include fatigue, loss of appetite, right upper abdominal pain, dark urine and jaundice. Any of these symptoms should be reported to your doctor for evaluation. It is important to remember that you should not stop taking a medication without consulting your doctor first. Discontinuing use of a prescribed drug can be far more dangerous than the side effect you're worried about. "All the side effects listed by the FDA are rare, and the risk of heart attack is far more concerning," Taber says. "Some patients may need extra monitoring or may need to try more than one statin before we find the optimal choice, but in general statins are very well tolerated and don't cause problems for the people who take them." The advice above is universal when it comes to your health. Concerns should be discussed with your doctor, and decisions should always be made as part of a team approach to creating a healthy life.

Read More

Why don't GPS warn you that statins can harm your memory?

John Holliday had been on a higher 40mg dose of cholesterol pills for only a few weeks when he started to lose his concentration. ‘I’d be watching TV and suddenly find myself unable to follow the plot of a drama,’ says John, 52, a telecoms project manager who lives in Southend-on-Sea, Essex, with his wife Jill, 51, and their two children Adam, 20, and Emma, 16. ‘I’d have to read the same page of a book over and over because I couldn’t take any information in. ‘I’d always been known for my amazing memory — I was great on trivia and had total recall of events that happened 20 years ago, but suddenly I couldn’t remember things and my brain felt fuzzy.’ Just like up to seven million other people in Britain, John had been prescribed a statin to lower his blood cholesterol levels. The drugs are credited by the British Heart Foundation as contributing towards the dramatic 50 per cent fall in deaths from heart attacks in the past ten years. But while there is consensus that statins are lifesavers for people who have previously had a heart attack, concern is growing over their debilitating side-effects. They include muscle weakness, depression, sleep disturbance, sexual dysfunction, muscle pain and damage, gastro-intestinal problems, headaches, joint pains and nausea. Now, official bodies here and in the U.S. have ordered that the drugs must carry warnings for cognitive problems, too. Worryingly, it’s claimed GPs are failing to warn patients of the effect statins can have on the mind — meaning they may mistake them for signs of ageing or Alzheimer’s. ‘When I went back to my doctor after six weeks for a blood test, I told him how dreadful I was feeling,’ says John. ‘But he just said all drugs had side-effects and didn’t mention reducing the dose.’ It's claimed GPs are failing to warn patients of the effect statins can have on the mind - meaning they may mistake them for signs of ageing or Alzheimer's Things came to a head when a friend showed John an electrical circuit he’d built for his car. ‘I’d worked with circuits since I was 16 but it made no sense,’ he says. So John insisted on seeing his doctor again and repeated his concerns about his rapidly declining memory. This time the GP told him he could start on another type of statin when he felt well enough, and so John stopped taking the drugs immediately. ‘It took a few months, but gradually my memory returned and I’ve got my concentration back. I can’t say for sure statins caused these problems, but it seems like too much of a coincidence.’ Earlier this year, the Food and Drug Administration (FDA) in the U.S. ordered statins must carry warnings that some users have reported cognitive problems including memory loss, forgetfulness and confusion. This followed a decision by the UK’s Medicines Healthcare Regulatory Agency (MHRA) to add memory problems to the list of  possible statin side-effects in late 2009. The FDA said reports about the symptoms were from across all statin products and age groups. Those affected reported feeling fuzzy or unfocused in their thought process — though these were found to be rare and reversible. The FDA also warned, following U.S. research, that patients on statins had a small excess risk of developing Type 2 diabetes — but stressed that the benefits of taking a statin still outweigh this. The MHRA had 2,675 reports for adverse drug reactions connected with statins between 2007 and 2011. Officially, side-effects are rare —affecting only 1 per cent of people on the pills — but some doctors say they are under-reported. Dr Malcolm Kendrick, a GP and author of The Great Cholesterol Con, says he frequently sees patients suffering from mental confusion in his job in hospital intermediary care for the elderly. ‘Many of the patients I see will have been admitted to hospital after a fall or similar crisis,’ he says. ‘If they appear confused I’ll often advise taking them off statins to see if it has any effect — in my experience, about 10 to 15 per cent of people who appeared to have memory problems experienced an improvement in their memory symptoms after being taken off the drug. ‘I had one dramatic case where a lady was admitted to hospital on 40mg a day of simvastatin with such poor memory function her family asked me about power of attorney. 'I suggested taking her off statins and within a week her memory had returned to normal. She went home a fit and independent 83-year-old.’ Dr Kendrick says cholesterol is the main constituent of synapses (structures that allow signals to pass between brain cells and to create new memories) and is essential for brain function. ‘It is still not proven that statins have a significant effect on mortality — it has been calculated that a man who has had a heart attack who took a statin for five years would extend his life by only 14 days. 'Too many statins are being given to people at low risk. ‘Even in the highest risk group you need to treat 200 people a year with statins to delay just one death. 'One day the harm these drugs are doing is going to be obvious — the benefits are being over-hyped and the risks swept under the carpet.’ While Dr Kendrick’s controversial view is in the minority, one large review of 14 studies by the London School of Hygiene and Tropical Medicine, published by the highly respected Cochrane Library last year, concluded there was ‘little evidence’ cholesterol-lowering drugs protect people who are not at risk of heart disease. This review has been criticised by other doctors who say side-effects are rare and that there are still benefits even for people at lower risk who do not have established heart disease. These defenders of statins include Professor Colin Baigent of the Clinical Trial Service at Oxford University, who published research in 2010 showing statins reduced deaths from all causes by 10 per cent over five years. ‘There is relatively little evidence of cognitive impairment — what evidence there is all comes from observational studies.  ‘People read about side-effects and then put two and two together and blame the statins for their muscle pain or other health problems — it’s just not reliable evidence. ‘If you look at the best-quality randomised controlled trial where patients don’t know if they are taking a statin or placebo, there is no evidence of memory problems. 'Even the FDA says the risks of cognitive problems are very small and go away when statins are discontinued. ‘We’re in danger of forgetting just how effective these drugs are.’ Dr Dermot Neely of the charity Heart UK, and lead consultant at the Lipid and Metabolic Clinic at the Royal Victoria Infirmary in Newcastle, agrees side-effects with statins are rare. ‘I’ve been dealing with patients on statins since 1987 and I can count on the fingers of one hand the number whose memory symptoms turned out to be caused by statins.’ However, he said he often saw patients who had not been told about side-effects. ‘It’s important GPs are clear about the drugs statins can interact with, such as certain antibiotics, as this can get overlooked. ‘If a patient notices an adverse effect after starting statins, they should discuss this with their GP —but not stop their drugs suddenly because this can be dangerous.’ Sonya Porter, 73, decided to stop taking statins after her memory problems became so bad that she walked away from a cashpoint leaving her money behind. ‘I was permanently fuzzy-headed and just couldn’t seem to concentrate,’ says Sonya, a retired PA from Woking, Surrey. Then I started to get scared I might have Alzheimer’s. After reading about memory problems associated with statins, I thought it was at least a possibility. I decided to come off the pills to see if it made any difference. ‘I didn’t ask my GP, I just did it — I’d rather die of a heart attack than Alzheimer’s disease. Within a month I felt normal again and didn’t have any problems with memory. ‘I’m terrified that I could have been misdiagnosed with Alzheimer’s.’ John Holliday is also reluctant to go back on statins. ‘I wouldn’t rule it out completely — my latest test showed my cholesterol levels have gone up,’ he says. ‘But on balance, I’d rather take my chances with heart disease than feel as confused as that again. It’s all very well living slightly longer — but it’s about quality of life, too.’

Read More

James Murdoch to resign as BSkyB chairman

James Murdoch is to step down as chairman of UK satellite broadcaster BSkyB, but will remain on the board. He is the son of News Corporation founder Rupert, whose company had to drop its bid for BSkyB after the phone-hacking scandal. In February, James Murdoch stepped down as chairman of News International, which publishes the Sun and the Times in the UK. He said then he had moved to New York to work on News Corp's pay-TV business. News Corp owns almost 40% of BSkyB and had wanted to buy the whole of the firm. But it withdrew its bid as political pressure mounted due to allegations of improper conduct at News International's News of the World Sunday title, which was shut down last July. Sources told Robert Peston, the BBC's business editor, that it was James Murdoch's decision to leave and he did so in an attempt to pre-empt further criticism as investigations continue into phone hacking. James Murdoch has repeatedly denied knowing about phone hacking at the News of the World. Nicholas Ferguson will take over as chairman.

Read More